Fadogia Agrestis
Fadogia Agrestis and Testosterone: What the Science Says
Fadogia agrestis, a shrub native to Nigeria, has garnered attention in the supplement industry for its purported ability to boost testosterone levels. While traditional use and some animal studies suggest potential benefits, the scientific evidence remains limited and primarily based on non-human research.(Hone Health, Back to Your Roots Herbs)
🧪 Animal Studies and Testosterone Production
The most cited study on Fadogia agrestis was published in the Asian Journal of Andrology in 2005. This research administered varying doses of an aqueous extract of Fadogia agrestis to male albino rats and observed significant increases in serum testosterone levels—twofold at 18 mg/kg, threefold at 50 mg/kg, and sixfold at 100 mg/kg—compared to controls. Additionally, the study noted an increase in testicular weight, suggesting enhanced reproductive function .(Back to Your Roots Herbs, Examine)
A subsequent study in 2008 by the same research team administered Fadogia agrestis extract to male rats over a 28-day period. While initial increases in testosterone were observed, levels declined below baseline by day five, and potential toxic effects on testicular tissue were noted at higher doses. These findings highlight the necessity for caution and further investigation into the safety and efficacy of Fadogia agrestis .(TestoFuel)
⚠️ Safety Concerns and Toxicity
Animal studies have raised concerns about the safety of Fadogia agrestis supplementation, particularly at higher doses. Research indicates potential toxicity to testicular cells and other organs, underscoring the importance of adhering to recommended dosages and considering cycling protocols to mitigate risks .(Luke Hall Nutrition, Dexa)
🔄 Dosage and Supplementation Practices
In the absence of standardized dosing guidelines, supplement manufacturers often recommend daily dosages ranging from 300 mg to 2,500 mg. However, these recommendations lack scientific validation. (Dexa)
✅ Conclusion
While initial animal studies indicate that Fadogia agrestis may have the potential to increase testosterone levels, the lack of human clinical trials and concerns about safety necessitate a cautious approach. Individuals interested in exploring this supplement should consult healthcare professionals, consider potential risks, and remain informed about the evolving scientific landscape surrounding its use.(Luke Hall Nutrition)
