Corynanthe Johimbe

Corynanthe Johimbe Bark and Testosterone: What the Science Really Says

If you've been exploring natural supplements to boost testosterone or enhance male performance, you've likely encountered Johimbe bark. Derived from the Pausinystalia johimbe tree native to West Africa, this herbal extract has long been used as an aphrodisiac. In modern times, it's marketed for testosterone enhancement, erectile function, fat loss, and energy. But does the science support these claims?

Let’s examine the evidence behind Yohimbe and its supposed testosterone-boosting powers.

What Is Corynanthe Johimbe?

Yohimbe is an evergreen tree found in Central and West Africa. The bark contains a compound called yohimbine, an alkaloid with stimulant and vasodilatory properties. Traditionally used to boost libido and sexual performance, it is now available in both prescription (yohimbine hydrochloride) and supplement forms (NCCIH, 2020).

What the Research Says

• Animal Study: A 2021 study in rats found that johimbine inhibited prostate enlargement by downregulating the enzyme 5α-reductase type 2, involved in testosterone metabolism. This suggests a potential hormonal interaction, though results in animals don’t always apply to humans (Okon et al., 2021).

• Human Study: In a clinical trial of 82 men with erectile dysfunction, some improvement in sexual performance was observed after yohimbine treatment, including in patients with low testosterone. However, this study did not demonstrate a direct increase in testosterone levels (Morales et al., 1987).

• Sexual Behavior: Research in male rats found johimbine increased sexual motivation independently of testosterone, suggesting its effects are more neurological than hormonal (Rodriguez-Manzo & Fernandez-Guasti, 1989).

Other Potential Benefits

Erectile Function

Johimbine has a documented role in improving erectile dysfunction, especially of psychogenic or mild vascular origin. According to a systematic review, yohimbine showed modest but significant improvements in erectile function compared to placebo (Cui et al., 2015).

Fat Loss and Performance

Some evidence suggests that yohimbine may aid fat loss during fasted exercise and enhance exercise motivation. A 2023 review noted improvements in strength-endurance and mood among resistance-trained men, though findings are mixed (King & Siedlik, 2023).

Risks and Side Effects

Johimbe can cause serious side effects, especially when taken in high doses or without medical supervision. Known risks include:

• Elevated heart rate and blood pressure

• Anxiety and irritability

• Insomnia

• Headaches and nausea

In some cases, high doses can cause heart attacks or seizures. Johimbe can also interact negatively with medications, including antidepressants, stimulants, and blood pressure drugs (NCCIH, 2020).

Additionally, over-the-counter supplements are often unreliable—many products contain variable or unlisted amounts of yohimbine (Cohen et al., 2015).

Final Thoughts

Corynanthe Johimbe bark is a powerful herbal compound with a rich traditional history. Its modern use is more focused on enhancing sexual function and possibly supporting fat loss

If you're considering Johimbe, speak with a healthcare provider, especially if you take medication or have cardiovascular concerns.

References

1. NCCIH – Yohimbe

2. Okon et al., 2021 – Yohimbine and BPH in Rats

3. Morales et al., 1987 – Yohimbine for Erectile Dysfunction

4. Rodriguez-Manzo et al., 1989 – Sexual Motivation in Rats

5. Cui et al., 2015 – Systematic Review of Yohimbine

6. King & Siedlik, 2023 – Yohimbine Review

7. Cohen et al., 2015 – Inaccurate Yohimbe Supplements

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